NeoTYPE® HRR Profile | NeoGenomics Laboratories

<p>The NeoTYPE HRR Profile analyzes 31 biomarkers through a combination of next-generation sequencing (NGS) and IHC as listed below. NGS (30 genes): ATM, ATR, BARD1, BRCA1, BRCA2, BRIP1, CDK12, CHEK1, CHEK2, FANCA, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCL, MLH1, MRE11A, MSH2, MSH6, NBN, PALB2, PMS2, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RAD54L, TP53 IHC (1 biomarker): PD-L1 LDT (tech-only available for PD-L1).</p>

Orderable Turn Around Time

14 Days

Keywords

HRR

homologous recombination repair pathway

Meta Description

<p>Homologous recombination repair (HRR) is a pathway where mutations in genes involved in the repair of double-stranded DNA breaks have lost the ability to repair DNA and thus may lead to diseases such as cancer.</p>

Orderable Biomarkers

NY Approved

True

Orderable Biomarkers JSON

{"DNA Sequencing": {"SNVs + Indels": ["BRCA2", "BRIP1", "PALB2", "RAD51C", "ATM", "ATR", "BARD1", "BRCA1", "CDK12", "CHEK1", "CHEK2", "FANCA", "FANCC", "FANCD2", "FANCE", "FANCF", "FANCG", "FANCL", "MLH1", "MRE11", "MSH2", "MSH6", "NBN", "PMS2", "RAD50", "RAD51", "RAD51B", "RAD51D", "RAD54L", "TP53"]}, "Immunohistochemistry (IHC)": {"Expression": ["PD-L1"]}}

Keywords string

HRR, homologous recombination repair pathway NeoTYPE® HRR Profile

Title URL

neotype-hrr-profile

TAT Details

NGS: 14 Days
IHC: Global: 2 Days
Tech-Only: 24 Hours

Storage and transportation

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.