Code
NTG-HRRX-02CX
Profile
Active-Compendium
81445x1; 88360x1
81445
Clinical
Oncology,Pathology
FFPE tissue: Paraffin block preferred. Please use 10% buffered formalin fixative. Do not use zinc fixatives.
Flag Active
True
Orderable Test Description
<p>Homologous recombination repair (HRR) is a DNA repair pathway involved in the repair of double‑stranded DNA breaks. The NeoTYPE HRR Profile evaluates HRR‑related biomarkers using next‑generation sequencing (NGS) and immunohistochemistry (IHC).<br><Br>
<b>NGS – SNVs / Indels (30 genes)</b><br><Br>
<b>IHC (1 biomarker)</b><br>
* PD‑L1<br>
* PD‑L1 LDT (tech‑only available)</p>
<b>NGS – SNVs / Indels (30 genes)</b><br><Br>
<b>IHC (1 biomarker)</b><br>
* PD‑L1<br>
* PD‑L1 LDT (tech‑only available)</p>
Orderable Turn Around Time
14 Days
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"DNA Sequencing": {"SNVs + Indels": ["ATM", "ATR", "BARD1", "BRCA1", "BRCA2", "BRIP1", "CDK12", "CHEK1", "CHEK2", "FANCA", "FANCC", "FANCD2", "FANCE", "FANCF", "FANCG", "FANCL", "MLH1", "MRE11", "MSH2", "MSH6", "NBN", "PALB2", "PMS2", "RAD50", "RAD51", "RAD51B", "RAD51C", "RAD51D", "RAD54L", "TP53"]}, "Immunohistochemistry (IHC)": {"Expression": ["PD-L1"]}}
Keywords string
HRR, homologous recombination repair pathway NeoTYPE® HRR Profile
Title URL
neotype-hrr-profile
TAT Details
NGS: 14 Days
IHC: Global: 2 Days
Tech-Only: 24 Hours
Storage and transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.