USP6 Rearrangement

Code
FSH-USPR-01AX
Test
Active-Compendium
88374x1 automated or 88377x1 manual
Clinical
Pathology
Bone marrow aspirate: N/A
Peripheral blood: N/A
Fresh, unfixed tissue: N/A
Fluids: N/A
Paraffin block: Send paraffin block. Also send circled H&E slide for tech-only (required).
Cut slides: H&E slide (required) plus 4 unstained slides cut at 4-5 microns. Circle H&E slide for tech-only. 
Reminder about decalcified specimens: Testing will be attempted but most decalcification solutions are incompatible with FISH. Limited acid decalcification.
Flag Active
True
Orderable Test Description
Probe(s): USP6 (17p13.2)
Disease(s): Nodular fasciitis, aneurysmal bone cysts
Orderable Turn Around Time
3-5 Days
Keywords
Meta Description
USP6 gene rearrangements (fusions) are found in nodular fasciitis, aneurysmal bone cysts, and other lesions. Presence of a USP6 rearrangement can help differentiate these from other neoplasms and malignancies.
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Structural Rearrangement(s)": ["USP6"]}}
Keywords string
Tre-2 USP6 Rearrangement
Title URL
usp6-rearrangement
Storage and transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.