Code
FSH-NHLF-03BX
Panel
Active-Compendium
88374x7 automated. Codes may differ if manual analysis is performed.
Clinical
Pathology
<p><b>Bone Marrow Aspirate:</b> 1-2 mL in sodium heparin tube. EDTA tube is acceptable.<br>
<b>Peripheral Blood:</b> 2-5 mL in sodium heparin tube. EDTA tube is acceptable.<br>
<b>Fresh, Unfixed Tissue:</b> Tissue in RPMI.<br>
<b>Bone Marrow/Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides:</b> Minimum 7 slides, labeled with specimen type.<br>
<b>Fluids:</b> Mix in equal parts with RPMI (specimen volume to RPMI ratio of 1:1).<br>
<b>Fixed Cell Suspension:</b> A client-prepared fixed cell suspension is acceptable if received in 3:1 Methanol:Glacial Acetic Acid.<br>
<b>H&E slide (required) plus paraffin block.</b><br>
<b>Cut Slides:</b> H&E slide (required) plus 9 unstained slides cut at 4-5 microns.<br>
<b>Cut Slides:</b> H&E slide (required) plus 3 unstained slides cut at 4-5 microns for single abnormalities.<br>
<b>Note for Tech Only clients:</b> Please circle H&E slide.</p>
<b>Peripheral Blood:</b> 2-5 mL in sodium heparin tube. EDTA tube is acceptable.<br>
<b>Fresh, Unfixed Tissue:</b> Tissue in RPMI.<br>
<b>Bone Marrow/Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides:</b> Minimum 7 slides, labeled with specimen type.<br>
<b>Fluids:</b> Mix in equal parts with RPMI (specimen volume to RPMI ratio of 1:1).<br>
<b>Fixed Cell Suspension:</b> A client-prepared fixed cell suspension is acceptable if received in 3:1 Methanol:Glacial Acetic Acid.<br>
<b>H&E slide (required) plus paraffin block.</b><br>
<b>Cut Slides:</b> H&E slide (required) plus 9 unstained slides cut at 4-5 microns.<br>
<b>Cut Slides:</b> H&E slide (required) plus 3 unstained slides cut at 4-5 microns for single abnormalities.<br>
<b>Note for Tech Only clients:</b> Please circle H&E slide.</p>
Flag Active
True
Orderable Test Description
<p>This panel is designed to detect key genetic abnormalities associated with non-Hodgkin lymphoma (NHL). It includes the following probes:<br><br>
ALK (2p23)<br>
BCL6 (3q27)<br>
MYC (8q24)<br>
CCND1/IgH t(11;14)<br>
IgH (14q32)<br>
IgH/BCL2 t(14;18)<br>
MALT1 (18q21)<br><br>
Test Customization: Probes may be ordered separately.</p>
ALK (2p23)<br>
BCL6 (3q27)<br>
MYC (8q24)<br>
CCND1/IgH t(11;14)<br>
IgH (14q32)<br>
IgH/BCL2 t(14;18)<br>
MALT1 (18q21)<br><br>
Test Customization: Probes may be ordered separately.</p>
Orderable Turn Around Time
3-5 Days
Keywords
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Translocation(s)": ["IgH (14q32)", "MALT1 (18q21)", "BCL2/IgH t(14;18)", "CCND1(BCL1)/IgH t(11;14)"], "Amplification(s)": ["MYC"], "Structural Rearrangement(s)": ["ALK", "BCL6"]}}
Keywords string
NHL, Non-Hodgkin's Lymphoma, FISH Non-Hodgkin's Lymphoma (NHL) FISH Panel
Title URL
non-hodgkin-s-lymphoma-nhl-fish-panel
Clinical Significance
The NHL FISH panel is used for the detection of chromosome aberrations observed in lymphoma.
Storage and transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. For fresh samples: refrigerate before shipping and ship same day as drawn whenever possible. Do not freeze. NYS clients please provide date and time of collection.