p53 | NeoGenomics Laboratories

Code

APH-PFTX-01AX

Test

Active-Compendium

88360 x 1

Clinical

Pathology

Preferred specimen (FFPE block): 
A formalin-fixed, paraffin-embedded (FFPE) tissue block is the preferred specimen type. Use 10% NBF fixative; do not use zinc or mercury fixatives. 

If submitting slides (instead of a block): 
Submit the following. All slides cut at 4-5 microns. Please use positively-charged slides and 10% NBF fixative. 
H&E slide: One (1) unbaked, unstained slide for H&E staining (required) 
Cut Slides: Two (2) positively charged unstained slides for each IHC test/antibody ordered 

Specimen identification: 
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.

Central nervous system (CNS)

Upper Aerodigestive tract

Mon, 01/13/2025 - 12:00

Wed, 04/01/2026 - 12:00

Immunohistochemistry (IHC)

Global

Tech Only

Flag Active

True

Orderable Test Description

The product of the p53 gene is a nuclear phosphoprotein that regulates cell proliferation. Excess accumulation of the mutant p53 gene product results in inactivation of its tumor suppressor function and cellular transformation. Overexpression of mutant p53 gene has also been associated with high proliferative rates and poor prognosis in breast, colon, lung, and brain cancer, as well as in some leukemias and lymphomas.

Orderable Turn Around Time

1-2 Days

Keywords

p53

TP53 expression

tumor protein 53

Meta Description

The product of the p53 gene is a nuclear phosphoprotein that regulates cell proliferation. Excess accumulation of the mutant p53 gene product results in inactivation of its tumor suppressor function and cellular transformation.

Orderable Biomarkers

TP53

NY Approved

True

Orderable Biomarkers JSON

{"Immunohistochemistry (IHC)": {"Expression": ["TP53"]}}

Keywords string

p53, TP53 expression, tumor protein 53 p53

Title URL

p53