BRAF Mutation Analysis by PCR | NeoGenomics Laboratories

Code

MOG-BMAX-01AX

Test

Active-Compendium

81210

Clinical

Oncology,Pathology

FFPE solid tumor tissue: Paraffin block is preferred. Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.
Peripheral blood: 5 mL in EDTA tube.
Bone marrow: 2 mL in EDTA tube.

Note: Test is DNA-based. Please select Extract & Hold - DNA if specimen hold service is desired.

Solid Tumors

Biliary tract

Central nervous system (CNS)

Mon, 01/13/2025 - 12:00

Wed, 01/22/2025 - 12:00

Molecular

Global

Flag Active

True

Orderable Test Description

BRAF Mutation Analysis Assay is based on PCR amplification and detection of target DNA using complementary primer pairs and oligonucleotide probes labeled with fluorsescent dyes. This assay is designed to detect V600 mutations E, K, D, R, and G. For solid tumors, tumor enrichment is performed before extraction. Expanded coverage for BRAF exons 11 & 15 is available in the RAS/RAF Panel. Testing is available separately or in combination with HRAS, KRAS, and NRAS in the RAS/RAF Panel.

Orderable Turn Around Time

7 Days

Keywords

Meta Description

Bi-directional sequencing of exon 15 of the BRAF gene, which includes qualitative detection of V600 mutations E, K, D, and others, plus other significant exon 15 mutations.

Extra Note

Please select extract & hold - DNA if specimen hold service is desired. Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

Orderable Biomarkers

BRAF

NY Approved

True

Orderable Biomarkers JSON

{"DNA Sequencing": {"SNVs + Indels": ["BRAF"]}}

Keywords string

BRAF, V600E, melanoma, mutation analysis, thyroid cancer, colon cancer, colorectal cancer BRAF Mutation Analysis by PCR

Title URL

braf-mutation-analysis-by-pcr