PDGFB Rearrangement (22q13)

Code
FSH-PDGB-01BX
Test
Active-Compendium
88374x1 automated or 88377x1 manual.
Clinical
Pathology
Paraffin Block: Send paraffin block. Also send circled H&E slide for tech-only (required).
Cut Slides: H&E slide (required) plus 4 unstained slides cut at 4-5 microns. Circle H&E slide for tech-only.
Bone Marrow Aspirate: N/A
Peripheral Blood: N/A 
Fresh, Unfixed Tissue: N/A
Fluids: N/A
Flag Active
True
Orderable Test Description
Probe(s): PDGFB (22q13.1)
Disease(s): Dermatofibrosarcoma protuberans (DFSP)
Orderable Turn Around Time
3-5 Days
Meta Description
Dermatofibrosarcoma protuberans (DFSP) commonly has the COL1A1-PDGFB fusion gene and other variants of PDGFB fusion that are related to DFSP pathogenesis and targeted therapies.
Extra Note

Use cold pack for transport, making sure cold pack is not in direct contact with specimen.

Orderable Biomarkers
NY Approved
False
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Structural Rearrangement(s)": ["PDGFB"]}}
Keywords string
PDGFB, DFSP, growth factor beta, sarcoma PDGFB Rearrangement (22q13)
Title URL
pdgfb-rearrangement-22q13