Code
FSH-PCMP-03BX
Panel
Active-Compendium
88374x7 automated or 88377x7 manual
Clinical
Pathology
Bone Marrow Aspirate: 1-2 mL sodium heparin tube. EDTA tube is acceptable.
Peripheral Blood: Plasma cell enrichment was not validated using peripheral blood; therefore, it is not recommended as a screening specimen unless increased plasma cells are seen on blood smear. 2-5mL sodium heparin tube. EDTA tube is acceptable.
Fresh, Unfixed Tissue: Tissue in RPMI
Bone Marrow/ Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: minimum 7 slides labeled with specimen type.
Fluids: Equal parts RPMI to specimen volume.
Fixed Cell Suspension: A client fixed cell suspension may be submitted for testing as long as it is received in 3:1 Methanol:Glacial Acetic Acid.
Paraffin Block or Cut Slide: N/A
Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Peripheral Blood: Plasma cell enrichment was not validated using peripheral blood; therefore, it is not recommended as a screening specimen unless increased plasma cells are seen on blood smear. 2-5mL sodium heparin tube. EDTA tube is acceptable.
Fresh, Unfixed Tissue: Tissue in RPMI
Bone Marrow/ Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: minimum 7 slides labeled with specimen type.
Fluids: Equal parts RPMI to specimen volume.
Fixed Cell Suspension: A client fixed cell suspension may be submitted for testing as long as it is received in 3:1 Methanol:Glacial Acetic Acid.
Paraffin Block or Cut Slide: N/A
Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Flag Active
True
Orderable Test Description
<p>Probes: 1p-, 1q+, iso(1q): CDKN2C (1p32), CKS1B (1q21) | FGFR3/IgH t(4;14) | CCND1/IgH t(11;14) | 13q- (13q14, 13q34) | IgH/MAF t(14;16) | IgH/MAFB t(14;20) |17p- (TP53 17p13.1, NF1 17q11.2) Probes may be ordered separately. Disease(s): Plasma cell myeloma, multiple myeloma. Note: Plasma cell enrichment will be performed on bone marrow samples unless our client directs us otherwise. (Peripheral blood is not recommended as a screening specimen unless increased plasma cells are seen on blood smear.) Specimens should be received in our laboratory within 72 hours of collection.</p>
Orderable Turn Around Time
3-5 Days
Keywords
Extra Note
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Translocation(s)": ["FGFR3/IgH t(4;14)", "MAFB/IgH t(14;20)", "MAF/IgH t(14;16)", "CCND1(BCL1)/IgH t(11;14)"], "Aneuploidy": ["1p-, 1q+, iso(1q)"], "CNVs": ["Chromosome 17"], "Deletion(s)": ["13q", "1p"]}}
Keywords string
PCM Prognostic Panel, Plasma Cell Myeloma Plasma Cell Myeloma Prognostic FISH Panel
Title URL
plasma-cell-myeloma-prognostic-fish-panel