Code
FSH-PCMF-03BX
Panel
Active-Compendium
88374x5 automated or 88377x5 manual without reflex; with reflex add 88374x4 automated or 88377x4 manual
Clinical
Pathology
Bone Marrow Aspirate: 1-2mL Sodium Heparin Tube. EDTA tube is acceptable
Peripheral Blood: Plasma cell enrichment was not validated using peripheral blood; therefore, it is not recommended as a screening specimen unless increased plasma cells are seen on blood smear. 2-5mL Sodium Heparin Tube. EDTA tube is acceptable
Fresh, Unfixed Tissue: Tissue in RPMI
Bone Marrow: Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: minimum 5 slides labeled with specimen type.
Fluids: Equal parts RPMI to specimen volume.
Fixed Cell Suspension: A client fixed cell suspension may be submitted for testing as long as it is received in 3:1 Methanol:Glacial Acetic Acid.
Paraffin Block or Cut Slide: N/A
Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Peripheral Blood: Plasma cell enrichment was not validated using peripheral blood; therefore, it is not recommended as a screening specimen unless increased plasma cells are seen on blood smear. 2-5mL Sodium Heparin Tube. EDTA tube is acceptable
Fresh, Unfixed Tissue: Tissue in RPMI
Bone Marrow: Peripheral Blood Smear or Fresh Tissue Touch Preparation Slides: minimum 5 slides labeled with specimen type.
Fluids: Equal parts RPMI to specimen volume.
Fixed Cell Suspension: A client fixed cell suspension may be submitted for testing as long as it is received in 3:1 Methanol:Glacial Acetic Acid.
Paraffin Block or Cut Slide: N/A
Note: Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Flag Active
True
Orderable Test Description
<p>Probes: 1p-, 1q+, iso(1q): CDKN2C (1p32), CKS1B (1q21) | +5, hyperdiploidy (5p15) | +9, hyperdiploidy (9q22) | +15, hyperdiploidy (15q22) | 13q- (13q14, 13q34) | IgH (14q32) | 17p- (TP53 17p13.1, NF1 17q11.2)Probes may be ordered separately except +5, +9 and +15 which are combined. Global cases with IgH rearrangement will automatically reflex to the Plasma Cell Myeloma IgH Complex FISH Panel unless client has opted out. Disease(s): Plasma cell myeloma, multiple myeloma. Note: Plasma cell enrichment will be performed on bone marrow samples unless our client directs us otherwise. (Peripheral blood is not recommended as a screening specimen unless increased plasma cells are seen on blood smear.) Specimens should be received in our laboratory within 72 hours of collection.</p>
Orderable Turn Around Time
3-5 Days. Add 3-5 Days if reflexed.
Keywords
Extra Note
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Aneuploidy": ["1p-, 1q+, iso(1q)"], "Translocation(s)": ["IgH (14q32)"], "Hyperdiploidy": ["Chromosome 5", "Chromosome 15", "Chromosome 9"], "Deletion(s)": ["13q"]}, "Deletion(s)": {"TP53 Deletion": ["TP53"]}}
Keywords string
plasmacytoma Plasma Cell Myeloma FISH Panel
Title URL
plasma-cell-myeloma-fish-panel