IGL/MYC t(8;22) translocation

Code
FSH-IGLM-01BX
Test
Active-Compendium
88374x1 automated or 88377x1 manual
Clinical
Pathology
Bone Marrow Aspirate: 1-2mL Sodium Heparin Tube. EDTA tube is acceptable
Peripheral Blood: 2-5mL Sodium Heparin Tube. EDTA tube is acceptable
Fresh, Unfixed Tissue: Tissue in RPMI
Bone Marrow/Peripheral Blood Smear or Fresh Tissue Preparation Slides: minimum 1 slide labeled with specimen type.
Fluids: Equal parts RPMI to specimen volume
Paraffin Block: H&E slide (required) plus paraffin block.  Circle H&E for tech-only.
Cut Slides: H&E slide (required) plus 2 unstained slides cut at 4 microns.  Circle H&E for tech only.
Flag Active
True
Orderable Test Description
Probes: IGL/MYC t(8;22)
Disease(s): B-cell lymphoma, double-hit lymphoma, triple-hit lymphoma
Orderable Turn Around Time
3-5 Days
Meta Description
IGL/MYC translocation is observed recurrently in B-cell lymphomas, and when occurred concurrently with BCL2 and/or BCL6 rearrangement, is classified as double-hit/triple-hit lymphomas having a very poor prognosis.
Extra Note

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Translocation(s)": ["IGK/MYC t(2;8)"]}}
Keywords string
MYC translocation, IGL translocation, lymphoma IGL/MYC t(8;22) translocation
Title URL
igl-myc-t8-22-translocation