DUSP22-IRF4 Rearrangement

Code
FSH-DUIR-01BX
Test
Active-Compendium
88374x1 automated or 88377x1 manual
Clinical
Pathology
Bone Marrow Aspirate: N/A
Peripheral Blood: N/A
Fresh, Unfixed Tissue: N/A
Fluids: N/A
Paraffin Block: H&E slide (required) plus paraffin block. Circle H&E for tech-only.
Cut Slides: H&E slide (required) plus 2 unstained slides cut at 4 microns. Circle H&E for tech-only.
Flag Active
True
Orderable Test Description
Probes: DUSP22-IRF4 gene region at 6p25.3
Disease(s): Anaplastic Large Cell Lymphoma (ALCL), large B-cell lymphoma
 
Orderable Turn Around Time
3-5 Days
Meta Description
The DUSP22-IRF4 Rearrangement FISH test detects translocations involving the DUSP22-IRF4 gene region as found in CD30-positive, ALK-negative ALCL, some large B-cell lymphoma, and some cases of lymphomatoid papulosis (LyP).
Extra Note

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Structural Rearrangement(s)": ["DUSP22", "IRF4"]}}
Keywords string
DUSP22, IRF4, DUSP22/IRF4, IRF4/DUSP22, plasma cell, cutaneous T-cell lymphoma, CTCL, MUM1 DUSP22-IRF4 Rearrangement
Title URL
dusp22-irf4-rearrangement