Tyrosinase

Code
APT-TYRX-01AX
Test
Active-Compendium
88342 x 1 or 88341 x 1 or 88341 x 1
Clinical
Pathology
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered.
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Flag Active
True
Orderable Test Description
Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this antibody showed tyrosinase in melanotic as well as amelanotic variants.
Orderable Turn Around Time
1 Day
Keywords
Meta Description
Tyrosinase is a copper-containing metalloglycoprotein that catalyzes many steps in the melanin pigment biosynthetic pathway. Tyrosinase is a target for cytotoxic T-cell recognition in melanoma patients. Its gene mutations occur in many forms of albinism.
Extra Note

Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.

Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Immunohistochemistry (IHC)": {"Expression": ["Tyrosinase"]}}
Keywords string
Tyrosinase Tyrosinase
Title URL
tyrosinase