Code
APT-ICOX-01AX
Test
Active-Compendium
88342x1 or 88341x1
Clinical
Pathology
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered.
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Flag Active
True
Orderable Test Description
ICOS (Inducible Co-Stimulator, CD278) is a member of the CD28 family that regulates T-cell activity and immune responses. ICOS is primarily expressed on activated CD4+ and CD8+ T-cells. It plays an important role in the diagnosis of T-cell lymphomas of follicular helper T-cell origin, and is useful when combined with multiple markers for follicular helper T-cells.
Orderable Turn Around Time
1 Day
Keywords
Extra Note
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Immunohistochemistry (IHC)": {"Expression": ["ICOS"]}}
Keywords string
ICOS, CD278, Inducible T Cell Costimulator ICOS
Title URL
icos