Code
APT-HTKX-01AX
Test
Active-Compendium
88342x1 or 88341x1
Clinical
Pathology
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen type or one (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody ordered.
Note: Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Note: Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Flag Active
True
Orderable Test Description
H3K27me3 (trimethylation at lysine 27 of histone H3) is involved in the modification of DNA by protein Histone H3. Complete loss of H3K27me3 expression by immunohistochemistry can be useful in the diagnosis of malignant peripheral nerve sheath tumors (MPNST).
Clone: C36B11
Staining pattern: Nuclear
Clone: C36B11
Staining pattern: Nuclear
Orderable Turn Around Time
1 Day
Extra Note
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Immunohistochemistry (IHC)": {"Expression": ["H3K27me3"]}}
Keywords string
BRG1 SMARCA4 SCCOHT ovarian cancer ovary carcinoma H3K27me3
Title URL
h3k27me3