Universal Solid Tumor NGS Fusion Panel | NeoGenomics Laboratories

Code

MOG-USTP-03AX

Panel

Active-Compendium

81456

81479

Clinical

Oncology,Pathology

FFPE tissue: Paraffin block is preferred. Alternatively, send 1 H&E slide plus 5-10 unstained slides cut at 5 or more microns. Please use positively-charged slides and 10% NBF fixative. Do not use zinc fixatives.

Mon, 01/13/2025 - 12:00

Fri, 05/09/2025 - 12:00

Next Generation Sequencing (NGS)

Global

Flag Active

True

Orderable Test Description

The Universal Solid Tumor NGS Fusion Panel is an RNA-based next-generation sequencing panel that detects translocations and fusions with known and novel fusion partners of these genes: ABL1, ACSL3, ACTB, ACTL6A, AFDN, AFF1, AFF3, AFF4, AHRR, AKAP9, AKT3, ALK, AR, ARID1A, ASPSCR1, ATF1, ATIC, AXL, BCOR, BCR, BRAF, BRCA1, BRCA2, BRD4, C11orf95, CAMTA1, CANT1, CAPZA2, CARS1, CBFA2T3, CCDC170, CCDC6, CCNB3, CCND1, CCND2, CCND3, CD274, CD74, CDH11, CDK4, CDK6, CDKN2D, CHCHD7, CIC, CIITA, CLTC, CNBP, COA5, COL1A1, COL1A2, CREB1, CREB3L1, CREB3L2, CREBBP, CRTC1, CRTC3, CSF1, CTLA4, CTNNB1, CTNNBL1, DDIT3, DDX3X, DDX5, DHH, DNAJB1, DUX4, EGFR, EGFRvIII, ELK4, ELL, EML4, EPC1, EPS15, ERBB2, ERG, ESR1, ESRP1, ETV1, ETV4, ETV5, ETV6, EWSR1, EZR, FAM131B, FEV, FGFR1, FGFR2, FGFR3, FGFR4, FLI1, FLT3, FOXO1, FOXP1, FRK, FUS, GLI1, GLIS1, GLIS2, GLIS3, GNAS, GOPC, HAS2, HERPUD1, HEY1, HIP1, HMGA2, HMGN2P46, HNRNPA2B1, IL2RB, IRF4, ITK, JAK2, JAZF1, KAT6A, KDM5A, KIAA1549, KIF5B, KIT, KLK2, KMT2A, KNL1, KRAS, LIFR, LMNA, LPP, MAML1, MAML2, MAST1, MAST2, MEAF6, MET, MET Exon 14 skipping, MKRN1, MLLT1, MLLT10, MLLT11, MLLT3, MN1, MPRIP, MRTFB, MSH2, MYB, MYBL1, MYC, MYH9, MYLK, NAB2, NCOA1, NCOA2, NCOA4, NDRG1, NFATC2, NFIB, NOTCH1, NOTCH2, NPM1, NR4A3, NRG1, NTRK1, NTRK2, NTRK3, NUP214, NUP98, NUTM1, NUTM2A, NUTM2B, OMD, PAN3, PATZ1, PAX3, PAX7, PAX8, PBX1, PCM1, PDGFB, PDGFRA, PDGFRB, PHF1, PIK3CA, PLAG1, PML, POU5F1, PPARG, PRCC, PRKACA, PRKAR1A, PRKD1, PRKD2, PRKD3, PTPRK, RAD51B, RAF1, RANBP2, RARA, RASGEF1A, RET, RHEBL1, ROS1, RPS6KC1, RSPO3, RUNX1, RUNX1T1, SDC4, SEC31A, SEPTIN6, SEPTIN9, SET, SLC34A2, SLC45A3, SND1, SNURF, SRF, SRGAP3, SS18, SSX1, SSX2, SSX4B, STAT6, STIL, STRN, SUZ12, SYK, TACC3, TAF15, TAL1, TBL1XR1, TCF12, TCF3, TCF7L2, TEAD1, TEAD2, TEAD3, TFE3, TFG, THADA, THRAP3, TMPRSS2, TP63, TPM3, TPM4, TPR, TRIM24, UBTF, USP6, VTI1A, WDFY2, WIF1, WT1, WWTR1, YAP1, YWHAE, and ZNF444 (total 250 genes and 2 variants).
 
As of May 12, 2025, this test serves as replacement for the following test(s) that are no longer offered:
<ul>
<li>Breast NGS Fusion Panel</li>
<li>Cholangio/Pancreatic Carcinoma NGS Fusion Panel</li>
<li>Colorectal NGS Fusion Panel</li>
<li>Lung Complete NGS Fusion Panel</li>
<li>Lung Limited NGS Fusion Panel</li>
<li>Prostate NGS Fusion Panel</li>
<li>Salivary Gland NGS Fusion Panel</li>
<li>Thyroid NGS Fusion Panel</li>
</ul>

Orderable Turn Around Time

21 Days

Keywords

Breast NGS Fusion Panel

Cholangio/Pancreatic Carcinoma NGS Fusion Panel

Colorectal NGS Fusion Panel

Lung Complete NGS Fusion Panel

Lung Limited NGS Fusion Panel

Prostate NGS Fusion Panel

Salivary Gland NGS Fusion Panel

Thyroid NGS Fusion Panel

Meta Description

The Universal Solid Tumor NGS Fusion Panel is an RNA-based NGS panel that detects translocations and fusions with known and novel fusion partners of genes associated with various solid tumors, esp. difficult-to-diagnose tumors of uncertain histogenesis.

Orderable Biomarkers

NY Approved

True

Orderable Biomarkers JSON

{"RNA Sequencing": {"Fusions": ["PATZ1", "PAX3", "PAX7", "PAX8", "PCM1", "PHF1", "PLAG1", "PML", "POU5F1", "PPARG", "PRCC", "PRKACA", "PRKAR1A", "PRKD1", "PRKD2", "PRKD3", "PTPRK", "RAD51B", "FGFR2", "RANBP2", "RARA", "RASGEF1A", "RHEBL1", "RPS6KC1", "RSPO3", "RUNX1T1", "SDC4", "SEC31A", "SEPTIN6", "SEPTIN9", "SET", "SLC34A2", "SLC45A3", "SND1", "SNURF", "SRF", "SRGAP3", "SS18", "SSX1", "SSX2", "SSX4B", "STIL", "STRN", "SUZ12", "SYK", "TAF15", "TBL1XR1", "TCF12", "TCF7L2", "TEAD1", "TEAD2", "THADA", "TEAD3", "TFE3", "ALK", "BRAF", "THRAP3", "CIC", "TMPRSS2", "EGFR", "TP63", "EML4", "EWSR1", "TPM4", "FGFR3", "FUS", "TRIM24", "KIAA1549", "UBTF", "MET", "MAML2", "MN1", "MYB", "WDFY2", "MYBL1", "WWTR1", "USP6", "YWHAE", "ROS1", "VTI1A", "ZNF444", "TACC3", "TFG", "YAP1", "TPM3", "RAF1", "FGFR4", "NOTCH1", "STAT6", "NRG1", "PDGFB", "RET", "TPR", "AKAP9", "NOTCH2", "BRCA1", "BRCA2", "CDK4", "MSH2", "ABL1", "MYH9", "BCR", "PIK3CA", "WIF1", "ETV6", "FGFR1", "FLT3", "WT1", "JAK2", "ACTB", "ACSL3", "KMT2A", "AFDN", "MLLT10", "AFF3", "NTRK1", "NTRK2", "AHRR", "NTRK3", "AKT3", "NUP98", "AFF1", "PBX1", "PDGFRA", "AFF4", "PDGFRB", "ARID1A", "ASPSCR1", "RUNX1", "ATF1", "TAL1", "ATIC", "TCF3", "AR", "AXL", "BCOR", "BRD4", "CAMTA1", "CANT1", "CAPZA2", "CARS1", "CBFA2T3", "CCDC170", "CCDC6", "CCNB3", "CCND1", "CCND2", "CCND3", "CD274", "CD74", "CDH11", "CDK6", "CDKN2D", "CHCHD7", "CIITA", "CLTC", "CNBP", "COA5", "COL1A1", "COL1A2", "CREB1", "CREB3L1", "CREB3L2", "CREBBP", "CRTC1", "CRTC3", "CSF1", "CTLA4", "CTNNB1", "CTNNBL1", "DDIT3", "DDX3X", "DDX5", "DHH", "DNAJB1", "DUX4", "ELK4", "ELL", "EPC1", "EPS15", "ERBB2", "ERG", "C11orf95", "ESR1", "ESRP1", "ETV1", "ETV4", "ETV5", "EZR", "FAM131B", "FEV", "FLI1", "FOXO1", "FOXP1", "FRK", "GLI1", "GLIS1", "GLIS2", "GLIS3", "GNAS", "GOPC", "HAS2", "HERPUD1", "HEY1", "HIP1", "HMGA2", "HMGN2P46", "HNRNPA2B1", "IL2RB", "IRF4", "ITK", "JAZF1", "KAT6A", "KDM5A", "KIF5B", "KIT", "KLK2", "KNL1", "KRAS", "LIFR", "LMNA", "LPP", "MAML1", "MAST1", "MAST2", "MEAF6", "MKRN1", "MLLT1", "MLLT11", "MLLT3", "ACTL6A", "MPRIP", "MRTFB", "MYC", "MYLK", "NAB2", "NCOA1", "NCOA2", "NCOA4", "NDRG1", "NFATC2", "NFIB", "NPM1", "NR4A3", "NUP214", "NUTM1", "NUTM2A", "NUTM2B", "OMD", "PAN3"], "Splice Variant": ["MET exon 14 Skipping", "EGFRvIII"]}}

Keywords string

solid tumor, gene fusion, gene rearrangement, NGSfusionsearch, Breast NGS Fusion Panel, Cholangio/Pancreatic Carcinoma NGS Fusion Panel, Colorectal NGS Fusion Panel, Lung Complete NGS Fusion Panel, Lung Limited NGS Fusion Panel, Prostate NGS Fusion Panel, Salivary Gland NGS Fusion Panel, Thyroid NGS Fusion Panel Universal Solid Tumor NGS Fusion Panel

Title URL

universal-solid-tumor-ngs-fusion-panel